Human health, animal health and food industry

Active Ingredient

Manufacturing for third parties

As leaders in DAO technology, we market two variants of the DAO active ingredient under the trade name of adiDAO®.

This active ingredient is suitable for the formulation of food supplements, or for addition to solid or liquid food matrices and is intended to treat the associated symptoms of Histamine intolerance caused by DAO Deficiency.


Thanks to ceaseless research in the extraction and purification of the enzyme, our active ingredient DAO is more efficient and has greater enzymatic activity and stability than competitive DAO extracts.

Therefore, we are pioneers in understanding Diamine Oxidase and are backed by 15+ years of research and development. We have a specific GMP-compliant enzymatic facility for the exclusive production of the active ingredient of animal- and plant- origin DAO, with physically separated production units.


Patent leaders

Our 100+ patents guarantee that customers receive the necessary protection in the commercialization of end products containing the DAO enzyme, granting them a unique legal protection no other supplier can offer.

DR Healthcare is world leader in DAO technology with more than 100 Industrial Property patents worldwide.

DR Healthcare’s DAO Industrial Property covers the management of DAO Deficiency and its DAO enzyme associated symptoms.

DR Healthcare’s Industrial Property protects the exclusive use of the DAO enzyme in a wide number of diseases and its galenic formulation worldwide.


Customized solutions

DR Healthcare stands out as a leading company in the production of Diamine Oxidase, which allows us to offer tailor-made solutions not only for use in human dietary supplements but also for use in the veterinary and food industry.

Our solutions based on Diamine Oxidase are adapted to the new food control regulations, which stipulate the control of histamine levels to avoid risks of intoxication due to the consumption of large quantities of this biogenic amine present in food.

Veterinary and animal health sector

Veterinary solutions based on Diamino Oxidase for the dietary management of histaminosis and DAO deficiency in domestic animals, livestock and aquaculture. Its health is that of all being vital to control the pathophysiological effects that trigger high levels of histamine.

Food industry sector

FAO and WHO and countries around the world have applied regulations that include the analysis of foods that may contain high levels of histamine and measures to prevent their production through proper conservation, processing and distribution.