Diamine Oxidase (DAO) the enzyme that breaks down histamine

The Science Behind Histamine & DAO

Histamine is a natural compound found in many everyday foods — such as citrus fruits, fermented vegetables, dairy products, seafood, meat, poultry, and wine — and it’s also produced by your body. It plays important roles in immune responses, digestion, and communication between cells. When you eat foods containing histamine, your body breaks it down in the small intestine using an enzyme called diamine oxidase (DAO).

When the amount of histamine you consume is more than your body can break down, some of it may enter the bloodstream and disrupt normal digestion. This can contribute to general discomforts linked to histamine sensitivity. A number of factors — including genetics, gut health, diet, and certain medications — can influence how effectively your body metabolises histamine.

DAOfood® Plus, DAOfood® & DAOfood® VEG

DAOfood® Plus, DAOfood® & DAOfood® VEG help support the breakdown of dietary histamine.

DAOfood® Plus, DAOfood® & DAOfood® VEG are dietary supplements that provide diamine oxidase (DAO), the enzyme responsible for breaking down histamine from food. They are formulated to support the normal digestion of dietary histamine by helping the body metabolise the histamine you ingest.

By supplying DAO that is structurally and functionally equivalent to the enzyme found naturally in the human body, DAOfood® Plus, DAOfood® & DAOfood® VEG help increase DAO activity and reduce the absorption of dietary histamine.

DAOfood® Plus helps support the breakdown of dietary histamine.

✔ Supports the metabolism of food‑derived histamine with high‑activity DAO. (1)

✔ Trusted leaders in DAO: backed by 18 years of science excellence.

✔ DAOfood® supports digestive health by helping the body break down dietary histamine and supporting normal DAO levels.

✔ EFICAPS® capsules contain gastro‑resistant tablets with controlled‑release DAO and immediate‑release Vitamin C and Quercetin.

✔ Provides supplemental DAO — the same enzyme the body naturally produces to break down histamine in the gut.(1)(2)

✔ Includes Quercetin and Vitamin C — as complementary ingredients. (6)

✔ The Diamine Oxidase (DAO) contained in DAOfood® Plus serves as a supportive solution to the same enzyme found naturally in the body that is responsible for metabolising histamine. Taking DAOfood® Plus before meals helps elevate the amount of DAO in the small bowel to support breakdown of dietary histamine. This adds to the processing in the digestive tract of the histamine found in different foods. (1)

Advanced EFICAPS® Technology

Ensures controlled release of DAO, Vitamin C, and Quercetin for optimal timing and absorption.

Four‑Part
Capsule Structure

Each capsule contains: Two gastro‑resistant DAO mini‑tablets (controlled intestinal release). One pellet with immediate‑release Vitamin C. One pellet with immediate‑release Quercetin.

Triple‑Action
Formula

Combines DAO enzyme with Quercetin and Vitamin C, acting as complementary ingredients.

Supports
Histamine Metabolism

Provides exogenous DAO enzyme to help break down food‑derived histamine in the small intestine.

Convenient
Daily Use

Easy‑to‑swallow capsules designed for use before meals to support normal digestion of histamine throughout the day.

DAOfood® helps support the breakdown of dietary histamine.

✔ Supports the metabolism of food‑derived histamine with high‑activity DAO.

✔ Trusted leaders in DAO: backed by 18 years of science excellence.

✔ DAOfood® supports digestive health by helping the body break down dietary histamine and supporting normal DAO levels.

✔ Gastro‑resistant mini‑tablets protect the DAO enzyme from stomach acidity so it can reach the small intestine intact.

✔ Provides supplemental DAO — the same enzyme the body naturally produces to break down histamine in the gut.

✔ The Diamine Oxidase (DAO) contained in DAOfood® serves as a supportive solution to the body’s own DAO, helping elevate DAO availability in the small bowel when taken before meals.

✔ Small, easy‑to‑swallow mini‑tablets in a convenient dispenser for everyday use at home or on the go.

Single‑Enzyme
Formula

Focused formula providing DAO only, for targeted dietary histamine breakdown.

Mini‑Tablet
Format

Each serving contains a gastro‑resistant DAO mini‑tablet for efficient intestinal release.

Gastro‑Resistant Technology

Mini‑tablets are engineered to withstand stomach acidity and ensure DAO is released where it is needed — the small intestine.

Supports Histamine Metabolism

Provides exogenous DAO enzyme to help break down food‑derived histamine in the small intestine.